Date Item Type No Grouping

Article

Optimization of protein loaded PLGA nanoparticles manufacturing parameters following a quality-by-design approach. (2016) Vanessa Sainz, Carina Peres, Tamara Ciman, Catarina Rodrigues, Ana Viana, Carlo A. M. Alfonso, Teresa S Barata, Steve Brocchini, Mire Zloh, Rogerio S. Gaspar, Helena Florindo and Joao Lopes description

Application of diffusion-edited and solvent suppression 1H NMR to the direct analysis of markers in valerian-hop liquid herbal products. (2016) Jose M. Prieto, Maria Mellinas-Gomez and Mire Zloh picture_as_pdf

In silico modelling of prostacyclin and other lipid mediators to nuclear receptors reveal novel thyroid hormone beta receptor antagonist properties. (2016) Noelia Perez Diaz, Mire Zloh, Pryank Patel and Louise Susan MacKenzie picture_as_pdf

Molecular modeling to study dendrimers for biomedical applications. (2014) Nuno Martinho, Helena Florindo, Liana Silva, Steve Brocchini, Mire Zloh and Teresa Barata

Rapid detection of sildenafil analogue in Eurycoma longifolia products using a new two-tier procedure of the near infrared (NIR) spectra database. (2014) Mazlina Mohd Said, Simon Gibbons, Anthony C. Moffat and Mire Zloh picture_as_pdf

A phytochemical comparison of saw palmetto products using gas chromatography and (1) H nuclear magnetic resonance spectroscopy metabolomic profiling. (2014) Anthony Booker, Andy Suter, Ana Krnjic, Brigitte Strassel, Mire Zloh, Mazlina Said and Michael Heinrich

A prodrug nanoparticle approach for the oral delivery of a hydrophilic peptide, leucine(5)-enkephalin, to the brain. (2012) Aikaterini Lalatsa, Vivian Lee, John P. Malkinson, Mire Zloh, Andreas G Schätzlein and Ijeoma F. Uchegbu picture_as_pdf

Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses. (2011) T.S. Barata, S. Brocchini, I. Teo, Mire Zloh and S. Shaunak

Molecular similarity of MDR inhibitors. (2004) Mire Zloh and S. Gibbons

Site-specific PEGylation of protein bisulfide bonds using a three-carbon bridge. (2007) S. Balan, A. Godwin, C.M. Laborde, S. Brocchini, J.-W. Choi, I. Teo, S. Shaunak, S. Heidelberger and Mire Zloh

Spectroscopic and conformational studies of the C-terminal cytoplasmic beta subunit 46-peptide of the high affinity IgE receptor. (1994) Mire Zloh, G. Anderson, I. Clark-Lewis, A. Nicolau, R. Thomas, I. Toth and W.A. Gibbons

Aryldiketo acids have antibacterial activity against MDR Staphylococcus aureus strains : Structural insights based on similarity and molecular interaction fields. (2009) B.J. Drakulić, M. Stavri, S. Gibbons, Ž.S. Žižak, T.Ž. Verbić, I.O. Juranić and Mire Zloh

The role of small molecule-small molecule interactions in overcoming biological barriers for antibacterial drug action. (2007) Mire Zloh and S. Gibbons

Site-specific PEGylation at histidine tags. (2012) Yuehua Cong, Estera Pawlisz, Penny Bryant, Sibu Balan, Emmanuelle Laurine, Rita Tommasi, Ruchi Singh, Sitara Dubey, Karolina Peciak, Matthew Bird, Amrita Sivasankar, Julia Swierkosz, Maurizio Muroni, Sibylle Heidelberger, Monika Farys, Farzad Khayrzad, Jeff Edwards, George Badescu, Ian Hodgson, Charles Heise, Satyanarayana Somavarapu, John Liddell, Keith Powell, Mire Zloh, Ji-won Choi, Antony Godwin and Steve Brocchini

Natural chalcones as dual inhibitors of HDACs and NF-κB. (2012) B. Orlikova, M. Schnekenburger, Mire Zloh, F. Golais, M. Diederich and D. Tasdemir

Sequences in the HSP90 promoter form G-quadruplex structures with selectivity for disubstituted phenyl bis-oxazole derivatives. (2012) Stephan A. Ohnmacht, Marialuisa Micco, Vanessa Petrucci, Alan K. Todd, Anthony P. Reszka, Mekala Gunaratnam, Marta A. Carvalho, Mire Zloh and Stephen Neidle

Prediction of aqueous solubility of drug-like molecules using a novel algorithm for automatic adjustment of relative importance of descriptors implemented in counter-propagation artificial neural networks. (2012) Slavica Erić, Marko Kalinić, Aleksandar Popović, Mire Zloh and Igor Kuzmanovski

Aconityl-derived polymers for biomedical applications : Modeling study of cis-trans isomerisation. (2003) Mire Zloh, E. Dinand and S. Brocchini

Spectroscopy-based modelling of the 3D structure of the β subunit of the high affinity IgE receptor. (2000) Mire Zloh, D. Esposito and W.A. Gibbons

Molecular dynamics simulations of proteins with chemically modified disulfide bonds. (2007) A. Godwin, E. Pedone, S. Balan, R. Jumnah, S. Brocchini, J.-W. Choi, S. Shaunak and Mire Zloh

Quantum chemical studies on structure activity relationship of natural product polyacetylenes. (2007) Mire Zloh, F. Bucar and S. Gibbons

Structural studies of biologically active glycosylated polyamidoamine (PAMAM) dendrimers. (2011) T.S. Barata, I. Teo, S. Shaunak, Mire Zloh and S. Brocchini

Mechanism of excitation and emission of papaverine molecule : fluorescence polarization spectroscopy study and MO calculation of transition moments. (1994) A.Dj. Aleksić, Mire Zloh and I. Juranić

Near-infrared spectroscopy (NIRS) and chemometric analysis of Malaysian and UK paracetamol tablets : A spectral database study. (2011) M.M. Said, S. Gibbons, A.C. Moffat and Mire Zloh

Role of complexes formation between drugs and penetration enhancers in transdermal delivery. (2008) B.J. Drakulić, I.O. Juranić, S. Erić and Mire Zloh

In silico screening for antibiotic escort molecules to overcome efflux. (2011) S.S. Rahman, I. Simovic, S. Gibbons and Mire Zloh

N.m.r. studies of the cytoplasmic C-terminal β-subunit domain of the high-affinity IgE receptor. (1994) Mire Zloh, G. Anderson, I. Clark-Lewis, R. Thomas, E. Benedetti, I. Toth and W.A. Gibbons

Identification and insertion of 3-carbon bridges in protein disulfide bonds : A computational approach. (2007) Mire Zloh, S. Shaunak, S. Balan and S. Brocchini

Target fishing and docking studies of the novel derivatives of aryl-aminopyridines with potential anticancer activity. (2012) S. Erić, J. Antić Stanković, V. Savić, S. Ke, T. Barata, T. Solmajer, Z. Juranić and Mire Zloh

C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes. (2012) Pietro Fratta, Sarah Mizielinska, Andrew J Nicoll, Mire Zloh, Elizabeth M. C. Fisher, Gary Parkinson and Adrian M. Isaacs

An analysis of the 'legal high' mephedrone. (2010) Simon Gibbons and Mire Zloh

Study of the selectivity of alpha(1)-adrenergic antagonists by molecular modeling of alpha(1a)-, alpha(1b)-, and alpha(1d)-adrenergic receptor subtypes and docking simulations. (2013) Slavica Eric, Tom Solmajer, Miha Kotnik, Mire Zloh and Danica Agbaba

NMR lipids profiles of common mushrooms. (1995) P. Bonzom, Mire Zloh, W. Baldeo, A. Nicolaou and W.A. Gibbons

Site-specific PEGylation of native disulfide bonds in therapeutic proteins. (2006) Sunil Shaunak, Antony Godwin, Ji-Won Choi, Sibu Balan, Elisa Pedone, Damotharan Vijayarangam, Sibylle Heidelberger, Ian Teo, Mire Zloh and Steve Brocchini

Synthesis of DNA-directed pyrrolidinyl and piperidinyl confined alkylating chloroalkylaminoanthraquinones : potential for development of tumor-selective N-oxides. (2006) Klaus Pors, Steven D. Shnyder, Paul H. Teesdale-Spittle, John A. Hartley, Mire Zloh, Mark Searcey and Laurence H. Patterson

PEGylation of native disulfide bonds in proteins. (2006) Steve Brocchini, Sibu Balan, Antony Godwin, Ji-Won Choi, Mire Zloh and Sunil Shaunak

Purification, characterisation and identification of acidocin LCHV, an antimicrobial peptide produced by Lactobacillus acidophilus n.v. Er 317/402 strain Narine. (2010) Hermine Mkrtchyan, Simon Gibbons, Sibylle Heidelberger, Mire Zloh and Hamidreza Khalatbari Limaki

Solid-phase synthesis of the cyclic peptide portion of chlorofusin, an inhibitor of p53-MDM2 interactions. (2003) John P. Malkinson, Mire Zloh, Mohanad Kadom, Rachel J. Errington, Paul J. Smith and Mark Searcey

Structure-activity relationships of monomeric C2-aryl pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumor agents. (2010) Dyeison Antonow, Maciej Kaliszczak, Gyoung-Dong Kang, Marissa Coffils, Arnaud C Tiberghien, Nectaroula Cooper, Teresa Barata, Sibylle Heidelberger, Colin H James, Mire Zloh, Terence C Jenkins, Anthony P Reszka, Stephen Neidle, Sylvie M Guichard, Duncan I Jodrell, John A Hartley, Philip W Howard and David E Thurston

Disulfide bridge based PEGylation of proteins. (2008) Steve Brocchini, Antony Godwin, Sibu Balan, Ji-won Choi, Mire Zloh and Sunil Shaunak

Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow. (2009) Faisal Ali, Mustafa Zakkar, Kersti Karu, Elaine A. Lidington, Shahir S. Hamdulay, Joseph J. Boyle, Mire Zloh, Andrea Bauer, Dorian O Haskard, Paul C. Evans and Justin C. Mason

Targeting glycolysis : a fragment based approach towards bifunctional inhibitors of hLDH-5. (2011) Adam D. Moorhouse, Christian Spiteri, Pallavi Sharma, Mire Zloh and John E. Moses

Preparation and characterisation of natamycin : gamma-cyclodextrin inclusion complex and its evaluation in vaginal mucoadhesive formulations. (2008) Erdal Cevher, Demet Sensoy, Mire Zloh and Lütfiye Mülazimoğlu

2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections. (2010) Deniz Tasdemir, David Sanabria, Ina L Lauinger, Alice Tarun, Rob Herman, Remo Perozzo, Mire Zloh, Stefan H. Kappe, Reto Brun and Néstor M Carballeira

Solution structure of a 2:1 C2-(2-naphthyl) pyrrolo[2,1-c][1,4]benzodiazepine DNA adduct : molecular basis for unexpectedly high DNA helix stabilization. (2008) Dyeison Antonow, Teresa Barata, Terence C. Jenkins, Gary N. Parkinson, Philip W. Howard, David E Thurston and Mire Zloh

From sequence to 3D structure of hyperbranched molecules : application to surface modified PAMAM dendrimers. (2011) Teresa S. Barata, Steve Brocchini, Ian Teo, Sunil Shaunak and Mire Zloh

Relative quantification of polyethylene glycol 400 excreted in the urine of male and female volunteers by direct injection electrospray-selected ion monitoring mass spectrometry. (2011) Diane A. I. Ashiru, Kersti Karu, Mire Zloh, Rajesh Patel and Abdul W. Basit

Disruption of D-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the {beta}-lactam resistance modifier (-)-epicatechin gallate. (2009) Patricia Bernal, Mire Zloh and Peter W. Taylor

Antibacterial acylphloroglucinols from Hypericum olympicum. (2012) Winnie K. P. Shiu, M. Mukhlesur Rahman, Jonathan Curry, Paul Stapleton, Mire Zloh, John P. Malkinson and Simon Gibbons

Direct metabolic fingerprinting of commercial herbal tinctures by nuclear magnetic resonance spectroscopy and mass spectrometry. (2009) Matteo Politi, Mire Zloh, Manuela E Pintado, Paula M L Castro, Michael Heinrich and Jose M Prieto

Putative DNA quadruplex formation within the human c-kit oncogene. (2005) Sarah Rankin, Anthony P. Reszka, Julian Huppert, Mire Zloh, Gary N. Parkinson, Alan K. Todd, Sylvain Ladame, Shankar Balasubramanian and Stephen Neidle

Spectroscopy and modelling of the cytoplasmic domain of the gamma-subunit of the high affinity immunoglobulin E receptor. (1994) G. J. Anderson, R. R. Biekofsky, Mire Zloh, G. K. Toth, I. Toth, E. Benedetti and W. A. Gibbons

Conformational studies of the beta-subunit of the high affinity IgE receptor : circular dichroism and molecular modelling. (1995) Mire Zloh, R. R. Biekofsky, J. A. Duret, M. Danton and W.A. Gibbons

Lipid-helix interactions in membrane receptors. (1996) Mire Zloh and W. A. Gibbons

Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells. (2006) Kerenza L. Njoh, Laurence H. Patterson, Mire Zloh, Marie Wiltshire, Janet Fisher, Sally Chappell, Simon Ameer-Beg, Yanhong Bai, Daniel Matthews, Rachel J. Errington and Paul J. Smith

NMR studies of the extracellular loop of the beta subunit of the high affinity IgE receptor. (1998) Mire Zloh, D. Esposito and W. A. Gibbons

Molecular modelling of the IgE receptor loops-lipid interaction. (1998) D. Esposito, Mire Zloh and W. A. Gibbons

Amanicadol, a pimarane-type diterpene from Phlomis amanica Vierch. (2006) F.N. Yalçin, T. Ersöz, I. Çaliş, E. Bedir, A.A. Dönmez, M. Stavri, S. Gibbons and Mire Zloh

Advanced microscopy solutions for monitoring the kinetics and dynamics of drug-DNA targeting in living cells. (2005) Rachel J. Errington, S. M. Ameer-Beg, B. Vojnovic, Laurence H. Patterson, Mire Zloh and P. J. Smith

Acid unfolding of beta-2-microglobulin by repulsion of + charges. (1988) P. Bray, M. Vucic, Mire Zloh and D. Vucelic

Isopimaric acid from Pinus nigra shows activity against multidrug-resistant and EMRSA strains of Staphylococcus aureus. (2005) Eileen Smith, Elizabeth Williamson, Mire Zloh and Simon Gibbons

The Effect of Phenyl Substituents on C-13 NMR Shifts and Metal Ions Binding to 4-Phenyl-2,4-Dioxobutanoic Acid Derivatives. (2008) Tatjana Z. Verbic, Branko J. Drakulic, Mire Zloh and Ivan O. Juranic

2β-Acetoxyferruginol - A new antibacterial abietane diterpene from the bark of Prumnopitys andina. (2008) E.C.J. Smith, S. Gibbons, N. Wareham and Mire Zloh

An LFER study of the protolytic equilibria of 4-aryl-2,4-dioxobutanoic acids in aqueous solutions. (2007) T.Ž. Verbić, J.R. Pecelj, I.O. Juranić, B.J. Drakulić, Mire Zloh and G.V. Popović

The effect of phenyl substituents on C NMR shifts and metal ions binding to 4-Phenyl-2,4-dioxobutanoic acid derivatives. (2009) T.Z. Verbić, I.O. Juranić, B.J. Drakulić and Mire Zloh

Direct NMR analysis of cannabis water extracts and tinctures and semi-quantitative data on delta9-THC and delta9-THC-acid. (2008) M. Politi, W. Peschel, N. Wilson, Mire Zloh, J. M. Prieto and M. Heinrich

Computational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex. (2011) T. Barata, I. Teo, S. Lalwani, E. Simanek, Mire Zloh and S. Shaunak

Cationic Poly-l-lysine Dendrimer Complexes Doxorubicin and Delays Tumor Growth in Vitro and in Vivo. (2013) Khuloud Al-Jamal, Wafa Al-Jamal, Julie T.-W. Wang, Noelia Rubio, Joanna Buddle, David Gathercole, Mire Zloh and Kostas Kostarelos

Efficient solid-phase-based total synthesis of the bisintercalator TANDEM. (2005) John P. Malkinson, Michael K. Anim, Mire Zloh, Mark Searcey, Andrew J. Hampshire and Keith R. Fox

β-Nitroso-o-Quinone Methides: Potent Intermediates in Organic Chemistry and Biology : The impact of the NO group on their Structure and Reactivity Profile: a Theoretical Insight. (2014) Pawel Kozielewicz, Petros Tsoungas, Mire Zloh, Demeter Tzeli and Ioannis Petsalakis

Investigation of the association and flexibility of cationic lipidic peptide dendrons by NMR spectroscopy. (2005) Mire Zloh, C. Ramaswamy, A. Wilderspin, T. Sakthivel and A.T. Florence

Antagonistic effects of indoloquinazoline alkaloids on antimycobacterial activity of evocarpine. (2015) C. Hochfellner, D. Evangelopoulos, Mire Zloh, A. Wube, J. D. Guzman, T. D. Mchugh, O. Kunert, S. Bhakta and F. Bucar

Correction to "Production of water-soluble few-layer graphene mesosheets by dry milling with hydrophobic drug". (2015) Noelia Rubio, Rui Serra-Maia, Houmam Kafa, Kuo-Ching Mei, Elzbieta Pach, William Luckhurst, Mire Zloh, Frederic Festy, Jonathan P. Richardson, Julian R. Naglik, Belén Ballesteros and Khuloud T. Al-Jamal

Computational classification models for predicting the interaction of drugs with P-glycoprotein and breast cancer resistance protein. (2014) S. Erić, M. Kalinić, K. Ilić and Mire Zloh

Arene-fused 1,2-oxazole N-oxides and derivatives. The impact of the N-O dipole and substitution on their aromatic character and reactivity profile. Can it be a useful structure in synthesis? A theoretical insight. (2014) Paweł Kozielewicz, Demeter Tzeli, Petros G. Tsoungas and Mire Zloh

Production of water-soluble few-layer graphene mesosheets by dry milling with hydrophobic drug. (2014) Noelia Rubio, Rui Serra-Maia, Houmam Kafa, Kuo Ching Mei, Khuloud T. Al-Jamal, William Luckhurst, Mire Zloh, Frederic Festy, Jonathan P. Richardson, Julian R. Naglik, Elzbieta Pach and Belén Ballesteros

Intramolecular cyclization of β-nitroso-o-quinone methides : A theoretical endoscopy of a potentially useful innate 'reclusive' reaction. (2015) Demeter Tzeli, Petros G. Tsoungas, Ioannis D. Petsalakis, Paweł Kozielewicz and Mire Zloh

Structural insights into binding of small molecule inhibitors to Enhancer of Zeste Homolog 2. (2014) Marko Kalinić, Mire Zloh and Slavica Erić

Crystal Structure of a Promoter Sequence in the B-raf Gene Reveals an Intertwined Dimer Quadruplex. (2013) Dengguo Wei, Alan K. Todd, Mire Zloh, Mekala Gunaratnam, Gary N. Parkinson and Stephen Neidle

Bioadhesive tablets containing cyclodextrin complex of Itraconazole for the treatment of vaginal candidiasis. (2014) Erdal Cevher, Ayşe Açma, Genada Sinani, Buket Aksu, Mire Zloh and Lütfiye Mülazımoğlu

Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates. (2004) Mire Zloh, G.W. Kaatz and S. Gibbons

Insights into mechanism of anticancer activity of pentacyclic oxindole alkaloids of Uncaria tomentosa by means of a computational reverse virtual screening and molecular docking approach. (2014) Pawel Kozielewicz, Katarzyna Paradowska, Slavica Eric, Iwona Wawer and Mire Zloh

Molecular dynamic simulations of ocular tablet dissolution. (2013) Qian Ru, Hala Fadda, Chung Li, Daniel Paull, Sir Peng Khaw, Stephen Brocchini and Mire Zloh

Potential of Lichen Secondary Metabolites against Plasmodium Liver Stage Parasites with FAS-II as the Potential Target. (2013) Ina L Lauinger, Livia Vivas, Remo Perozzo, Christopher Stairiker, Alice Tarun, Mire Zloh, Xujie Zhang, Hua Xu, Peter J. Tonge, Scott G. Franzblau, Duc-Hung Pham, Camila V. Esguerra, Alexander D. Crawford, Louis Maes and Deniz Tasdemir

Investigation of the protein alkylation sites of the STAT3:STAT3 inhibitor Stattic by mass spectrometry. (2013) Sibylle Heidelberger, Giovanna Zinzalla, Dyeison Antonow, Samantha Essex, B. Piku Basu, Jonathan Palmer, Jarmila Husby, Paul J. M. Jackson, Khondaker M. Rahman, Andrew F. Wilderspin, Mire Zloh and David E. Thurston

Hydrophobic core and surface charges of human beta-2-microglobulin probed by CD measurements. (1992) M. Vucic, P. Bray, Mire Zloh and D. Vucelic

Conference or Workshop Item

Identification of new psychoactive substances using Raman spectroscopy: handheld and computational approaches. (2016) Amira Guirguis, Stewart Kirton, Mire Zloh, Eleftherios Samaras, Sarah Girotto, Benedetta Berti and Jacqueline Stair description

Other

Synthesis and evaluation of antibacterial activity of series of novel diketones. (2015) Sharon Rossiter, Mire Zloh, Jatinder Bassin, Jagbir Singh and Madhu Goyal

In Silico Screening of Escort Molecules that Complex with Antibiotics. (2010) S.S. Rahman, S. Gibbons and Mire Zloh

Lipid mimetics : the design and properties of conformationally-restricted arachidonic acid lipidic and peptidic analogues. (1997) P. M. Bonzom, Mire Zloh, R. E. Reid and W.A. Gibbons

NMR-based modelling revealed an alpha helical structure for cytoplasmic domain of the alpha subunit of Fc epsilon RI, the high affinity IgE receptor. (1997) Mire Zloh, R. Thomas, R. E. Reid and W.A. Gibbons

Structural Studies on Glycosylated PAMAM Dendrimers. (2010) Teresa S. Barata, Steve Brocchini, Ian Teo, Sunil Shaunak and Mire Zloh

The role of complex formation between inhibitors and substrates of efflux pumps in bacteria. (2009) S.S. Rahman, K. Chary, M. Antoun, S. Gibbons and Mire Zloh

Chemometrics analysis of solid herbal products and development of spectral databases. (2010) Mazlina M. Said, Simon Gibbons and Mire Zloh

Metabolomic profiling of saw palmetto products using proton-NMR spectroscopy and multi-variate analysis. (2011) A. J. Booker, Mire Zloh, M. Said, A. Suter and M. Heinrich

Qualitative comparison of Malaysian and UK paracetamol tablets by Near-Infra Red. (2009) M. M. Said, S. Gibbons and Mire Zloh