Author
Number of items: 36.
2015
Design, Synthesis and Antimicrobial Evaluation of the in vitro Efficacy of Novel Diketones. (2015)
Rajesh Garikipati,
Olufunmilayo Mohammed,
Sharon Rossiter,
Simon Baines,
Jatinder Bassin
and
Madhu Goyal
In vitro assessment of Clostridium difficile PCR ribotype 002: the most prevalent C. difficile ribotype in the United Kingdom. (2015)
Simon Baines,
Iye Ameh,
Jane Freeman,
W N Fawley
and
M. H. Wilcox
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Antimicrobial resistance and reduced susceptibility in Clostridium difficile: potential consequences for induction, treatment, and recurrence of C. difficile infection. (2015)
Simon D. Baines
and
M. H. Wilcox
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In vitro susceptibility of Clostridium difficile to SMT19969 and comparators, as well as the killing kinetics and post-antibiotic effects of SMT19969 and comparators against C. difficile. (2015)
D. Corbett,
A. Wise,
S. Birchall,
P. Warn,
Simon D. Baines,
G. Crowther,
J. Freeman,
C. H. Chilton,
J. Vernon,
M. H. Wilcox
and
R. J. Vickers
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SMT19969 as a treatment for Clostridium difficile infection : an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model. (2015)
Simon D. Baines,
G. S. Crowther,
J. Freeman,
S. Todhunter,
R. Vickers
and
M. H. Wilcox
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2014
Comparison of planktonic and biofilm-associated communities of Clostridium difficile and indigenous gut microbiota in a triple-stage chemostat gut model. (2014)
Grace S. Crowther,
Caroline H. Chilton,
Sharie L. Todhunter,
Scott Nicholson,
Jane Freeman,
Simon D. Baines
and
Mark H. Wilcox
Development and validation of a chemostat gut model to study both planktonic and biofilm modes of growth of Clostridium difficile and human microbiota. (2014)
Grace S. Crowther,
Caroline H. Chilton,
Sharie L. Todhunter,
Scott Nicholson,
Jane Freeman,
Simon D. Baines
and
Mark H. Wilcox
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2013
In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. difficile infection. (2013)
C. H. Chilton,
G. S. Crowther,
Simon D. Baines,
S. L. Todhunter,
J. Freeman,
H. H. Locher,
A. Athanasiou
and
M. H. Wilcox
Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease. (2013)
David W. Eyre,
A. Sarah Walker,
Jane Freeman,
Simon D. Baines,
Warren N. Fawley,
Caroline H. Chilton,
David Griffiths,
Alison Vaughan,
Derrick W. Crook,
Tim E. A. Peto
and
Mark H. Wilcox
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Evaluation of NVB302 versus vancomycin activity in an in vitro human gut model of Clostridium difficile infection. (2013)
Grace S Crowther,
Simon D. Baines,
Sharie L Todhunter,
Jane Freeman,
Caroline H Chilton
and
Mark H Wilcox
Evaluation of antimicrobial activity of ceftaroline against Clostridium difficile and propensity to induce C. difficile infection in an in vitro human gut model. (2013)
Simon D. Baines,
Caroline H. Chilton,
Grace S. Crowther,
Sharie L. Todhunter,
Jane Freeman
and
Mark H. Wilcox
Evaluation of the effect of oritavancin on Clostridium difficile spore germination, outgrowth and recovery. (2013)
C. H. Chilton,
J. Freeman,
Simon D. Baines,
G. S. Crowther,
S. Nicholson
and
M. H. Wilcox
Mixed infection by Clostridium difficile in an in vitro model of the human gut. (2013)
Simon D. Baines,
Grace S. Crowther,
Sharie L. Todhunter,
Jane Freeman,
Caroline H. Chilton,
Warren N. Fawley
and
Mark H. Wilcox
2011
Efficacy of novel antimicrobial agent SMT-19969 (SMT) against simulated Clostridium difficile infection in an in vitro human gut model. (2011)
Simon D. Baines,
J. Freeman,
Grace S. Huscroft,
Sharie L. Todhunter,
M. H. Wilcox
and
R. Vickers
SASP: targeted delivery to Gram-negative pathogens. (2011)
H. Wang,
K. Hatzixanthis,
A. Barnard,
R. Shah,
E. Saveri,
K. Pitts,
D. Piwowarczyk,
G. Patil,
Simon D. Baines,
A. Wilkinson
and
H. Fairhead
SMT19969 – a novel antibiotic for C. difficile : Clostridium difficile growth inhibition, spectrum of activity and resistance development. (2011)
R. Vickers,
J. Tinsley,
R. Storer,
F. Wilson,
C. Dorgan,
S. Wren,
M. H. Wilcox,
Simon D. Baines
and
J. Freeman
Short-term genomic stability of Clostridium difficile within patients and a gut model. (2011)
D. W. Eyre,
C. Ip,
R. M. Harding,
J. Freeman,
Simon D. Baines,
W. N. Fawley,
S.D. Walker,
D. W. Crook,
T. E. A. Peto
and
M. H. Wilcox
Evaluation of linezolid for the treatment of Clostridium difficile infection caused by epidemic strains using an in vitro human gut model. (2011)
Simon D. Baines,
Alan R. Noel,
Grace S. Huscroft,
Sharie L. Todhunter,
Rachael O'Connor,
Joanne K. Hobbs,
Jane Freeman,
Andy M. Lovering
and
M. H. Wilcox
Nitazoxanide is active against Clostridium difficile strains with reduced susceptibility to metronidazole. (2011)
Jane Freeman,
Simon D. Baines,
Sharie L. Todhunter,
Grace S. Huscroft
and
M. H. Wilcox
2009
Activity of vancomycin against epidemic Clostridium difficile strains in a human gut model. (2009)
Simon D. Baines,
Rachel O'Connor,
Katie Saxton,
Jane Freeman
and
M. H. Wilcox
Characterization of the sporulation initiation pathway of Clostridium difficile and its role in toxin production. (2009)
Sarah Underwood,
Shuang Guan,
Vinod Vijayasubhash,
Simon D. Baines,
Luke Graham,
Richard J. Lewis,
M. H. Wilcox
and
Keith Stephenson
Effects of exposure of Clostridium difficile PCR ribotypes 027 and 001 to fluoroquinolones in a human gut model. (2009)
Katie Saxton,
Simon D. Baines,
Jane Freeman,
Rachael O'Connor
and
M. H. Wilcox
Mecillinam : a low-risk antimicrobial agent for induction of Clostridium difficile infection in an in vitro human gut model. (2009)
Simon D. Baines,
Rachael O'Connor,
Grace Huscroft,
Katie Saxton,
Jane Freeman
and
Mark H Wilcox
Tolevamer is not efficacious in the neutralization of cytotoxin in a human gut model of Clostridium difficile infection. (2009)
Simon D. Baines,
Jane Freeman
and
M. H. Wilcox
2008
Comparison of oritavancin versus vancomycin as treatments for clindamycin-induced Clostridium difficile PCR ribotype 027 infection in a human gut model. (2008)
Simon D. Baines,
Rachael O'Connor,
Katie Saxton,
Jane Freeman
and
Mark H. Wilcox
Emergence of reduced susceptibility to metronidazole in Clostridium difficile. (2008)
Simon D. Baines,
Rachael O'Connor,
Jane Freeman,
Warren N Fawley,
Celine Harmanus,
Paola Mastrantonio,
Ed J. Kuijper
and
M. H. Wilcox
In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin. (2008)
Rachael O'Connor,
Simon D. Baines,
Jane Freeman
and
Mark H. Wilcox